Session II:

Afib Detection and Personalized Stroke Prevention Approaches in Atrial Fibrillation

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1) What is the prominent pathology seen on the MRI below?

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A) Enlarged perivascular spaces
B) Microinfarcts
C) Severe white matter disease
D) None of the above
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tmb MassGen 2020 af detection intro pres

2) In a cohort of intracerebral hemorrhage patients, lobar lacunes are more common in those with presumed cerebral amyloid angiopathy; while deep lacunes are more frequent in patients with intracerebral hemorrhage of presumed hypertensive etiology.

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A) True
B) False
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3) Which statement is accurate surrounding cerebral microinfarcts?

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A) Small lesions of presumed ischemic origin that by default are invisible to the naked eye
B) First reported in neuropathological studies
C) No definitive size criteria but reported to be 1 mm to a few mm
D) All of the above
E) None of the above
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4) Which patient would be least likely to have significant white matter disease on brain MRI?

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A) 72 yo patient with cerebral amyloid angiopathy
B) 70 yo patient who had hypertensive deep brain hemorrhage
C) 25 yo patient with urinary tract infection
D) 50 yo patient with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
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5) How can a silent brain infarction be differentiated from an acute ischemic stroke?

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A) Silent brain infarction is never acute appearing on MR brain
B) Silent brain infarction is a transient episode of neurological dysfunction
C) Silent brain infarction is imaging or neuropathological evidence of infarction without a history of neurological dysfunction attributable to lesion
D) Acute ischemic stroke is always a diagnosis of exclusion
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6) What are some of the advantages of MR brain in diagnosing neurological symptoms?

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A) Distinguishing ischemia from subacute/chronic hemorrhage
B) Detecting small infarctions
C) Superior to Head CT in identifying acute ischemic stroke
D) All of the above
E) A and B only
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7) On MR brain, multiple infarcts in a single vascular territory are most suggestive of which ischemic stroke mechanism?

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A) Cardioembolism
B) Lacunar stroke
C) Large vessel atherosclerotic disease
D) Cryptogenic
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8) Multiple infarcts in different vascular territories seen in the MRI below are most suggestive of which ischemic stroke mechanism?

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A) Cardioembolism
B) Lacunar stroke
C) Large vessel atherosclerotic disease
D) Cryptogenic
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9) Where do clots form in the majority of patients with AF?

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A) Atrium
B) Left atrial appendage
C) Aortic arch
D) Aortic valve
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10) What markers of left atrial appendage dysfunction is associated with increased stroke risk in patients with AF?

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A) Morphology
B) Left atrial appendage flow velocity
C) Left atrial appendage spontaneous echocardiographic contrast
D) All of the above
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Background

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Considering my experience and background, the material presented was:

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Extent to which activity met the identified objectives
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Evaluate detection/rating of white matter disease, lacunes, microinfarcts and EPVS.

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Review detection and etiologic classification of symptomatic and “silent” cerebral infarcts.

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Discuss the role of the left atrial appendage in NVAF-related thrombus formation.

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Information Presented
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Reinforced my current practice/treatment habits: