Stroke Risk Reduction with LAA Closure: A Meta-Analysis of Randomized Trials

Activity Description
This CME-accredited on-demand webinar features a multidisciplinary panel of experts who thoroughly review an updated meta-analysis of randomized controlled trials comparing Left Atrial Appendage Closure (LAAC) with oral anticoagulation in patients with atrial fibrillation. The discussion focuses on efficacy and safety, including bleeding risks such as clinically relevant non-major bleeding, and on stroke characterization data. The faculty evaluate how these results can inform personalized, patient-centered decisions by weighing stroke and bleeding risks.

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Agenda

Agenda

Welcome and Introductions

Left Atrial Appendage Closure vs. Oral Anticoagulation in Atrial Fibrillation: A Meta-analysis of Randomized Trials
Vivek Reddy, MD

Panel Discussion with Q&A Session
Topics Covered:

Key Findings Review & Assessments from the Meta-analysis of Randomized Trials
- Bleeds, including Clinically Relevant Non-Major Bleeding
- Stroke Characterization Data

Moderator: Shephal Doshi, MD
Panel: Vivek Reddy, MD, C. Michael Gibson, MD, and Eugene Scharf, MD

Commercial Support
This activity is supported through an educational grant from:
Boston Scientific

Joint Providership:
MediaSphere Medical, LLC, and Ciné-Med

Faculty

Faculty
	Shephal Doshi, MD Cedars-Sinai Smidt Heart Santa Monica, CA	Vivek Reddy, MD The Mount Sinai Fuster Heart Hospital New York, NY
	C. Michael Gibson, MD Baim and PERFUSE Research Institutes Harvard Medical School Boston, MA	Eugene Scharf, MD Mayo Clinic Rochester, MN

CME Accreditation

CME Released: 9/25/2026; Valid for credit through 9/25/2027

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On-Demand Webinar: Claiming CME Credits and Certificate Fulfillment
Participants in the on-demand webinar can earn credits after watching the video and completing the online credit and evaluation form, which must be submitted within the credit period specified above. After viewing the video, click the Claim Credit button to complete the online credit and evaluation form. Once submitted, you can download or print the certificate.

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Live Webinar: Claiming CME Credits and Certificate Fulfillment
CME credits are available for the live webinar by submitting the online credit and evaluation form. Participants must submit the form by September 25, 2027, to earn Continuing Medical Education credit. Once submitted, you can download or print the certificate.

Important: Claiming Credit Note: Participants who claim CME credits for live webinar attendance are not eligible to claim credits for on-demand webinars.

Target Audience
This activity has been developed to meet the educational needs of Electrophysiologists, Cardiologists, Neurologists, Fellows-In-Training, allied healthcare professionals, and other physician groups interested in managing patients with Atrial Fibrillation who are at heightened stroke risk.

Learning Objectives
Upon completion of this educational activity, participants will be able to:

Compare stroke and bleeding outcomes from a meta-analysis of randomized trials comparing LAAC to OAC.
Assess how outcomes data can inform personalized, patient-centered decisions by weighing the risks of stroke and bleeding.

Accreditation Statement
Jointly Accredited Provider TM This activity has been planned and implemented by MediaSphere Medical and Ciné-Med to improve patient care. Ciné-Med is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Physicians. The activity is accredited for a maximum of 1 AMA PRA CATEGORY 1 Credits™ for Physicians. Nurses and Other Healthcare Professionals. All other healthcare professionals will receive a Certificate of Participation. Consult your professional licensing board for information on the applicability and acceptance of Certificates of Participation for activities designated for AMA PRA Category 1 Credits™.

Disclosure Policy
MediaSphere Medical and Ciné-Med adheres to accreditation requirements concerning industry support of continuing medical education. Speakers are required to openly disclose any limitations of data and/or any discussion of any off-label, experimental, or investigational uses of drugs or devices in their presentations. Speakers will disclose any relationships at the beginning of their presentations.
All MediaSphere Medical and Ciné-Med employees in control of content have indicated that they have no relevant financial relationships to disclose.

It is the policy of MediaSphere Medical and Ciné-Med to ensure balance, independent objectivity, and scientific rigor in all its supported educational programs. All faculty members participating in educational activities are required to disclose to the program audience any real of apparent conflicts of interest held within the past 12 months.

MediaSphere Medical and Ciné-Med implement a mechanism to identify and resolve all conflicts of interest prior to delivering the educational activity to learners.

Non-Endorsement Statement
MediaSphere Medical and Ciné-Med verify that sound education principles have been demonstrated in the development of this educational offering as evidenced by the review of its objectives, teaching plan, faculty, and activity evaluation process. MediaSphere Medical and Ciné-Med does not endorse or support the actual opinions or material content as presented by the speaker(s) and/or sponsoring organization.

Commercial Support
This activity is supported through an educational grant from:
Boston Scientific

Joint Providership:
MediaSphere Medical, LLC, and Ciné-Med