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Activity Description

The webcast is comprised of the proceedings from the satellite symposium held at Heart Rhythm 2015, Stroke Prevention in Atrial Fibrillation: Advancements in LAA Closure and Novel Oral Anticoagulation Therapy.

Enjoy this web-based version of the symposium, which captures the live cases, lectures, debates, and interactive panel discussions from the symposium in HD video.

Cardiac Rhythm Management

Access Webcast

Access Webcast

Click on the session title listed below to view each presentation.

Welcome and Opening Remarks

Vivek Reddy




Session I - AF-Related Stroke & Anticoagulation

Moderators: Daniel Singer and John Camm

Stroke vs Bleeding in AF: Using Risk Scores in Clinical Practice

Jeremy Ruskin


Peri-procedural Management of NOACs

Luigi Di Biase

Atrial Scarring & LAA Morphology: The Future of Risk Stratification?

Nassir Marrouche


Device-Detected Atrial High Rate Episodes: Risk and Management

John Camm

Selecting the Right NOAC for the Right Patient

Daniel Singer


Management of Cryptogenic Stroke: ILRs and Anticoagulation

Carlos Morillo

Overcoming a Barrier to the Novel Anticoagulants: Development of Antidotes

Michael Ezekowitz


Questions & Discussions

Jeremy Ruskin, Nassir Marrouche, Carlos Morillo, Michael Ezekowitz,
Luigi Di Biase, John Camm, Daniel Singer


Session II - Watchman

Moderator: Vivek Reddy

Watchman Implantation: Tips and Tricks

Shephal Doshi

Watchman Implantation – Case 1

Broadcast from Mount Sinai Hospital
Operators: Srinivas Dukkipati and Marc Miller
Panel: Shephal Doshi, Daniel Lustgarten, Petr Neuzil, Vivek Reddy, Tom DePotter, Miguel Valderrabano


Session III - Amplatzer Cardiac Plug

Moderators: Vivek Reddy and Moussa Mansour

Amplatzer Cardiac Plug Implantation: Step-By-Step

Boris Schmidt


Device Embolization – Incidence and Management

Claudio Tondo

Amplatzer Amulet Implantation Case

Broadcast from CardioVascular Center Frankfurt
Operator: Horst Sievert
Panel: Boris Schmidt, Claudio Tondo, Vivek Reddy, Moussa Mansour, Petr Neuzil


Session IV - LAA Closure Clinical Outcomes

Moderators: John Camm and Andre d’Avila

Watchman Randomized Trials: 5-yr PROTECT AF, PREVAIL

Vivek Reddy


Lariat: Clinical Outcomes

Dhanunjaya Lakkireddy

Watchman Registry Data: CAP/CAP-2, ASAP, EWOLUTION, WASP

Daniel Lustgarten


Atriclip: Clinical Outcomes

Christopher Ellis

Amplatzer Cardiac Plug: Single & Multicenter Registry Outcomes

Thorsten Lewalter



Questions & Discussion

Dhanunjaya Lakkireddy, Christopher Ellis, Thorsten Lewalter, Daniel Lustgarten,
Vivek Reddy, John Camm, Andre d’Avila


Session V –Live Case and Presentations

Moderator: Vivek Reddy

Post-LAA Closure Leaks – Incidence and Management

Jose Mauricio Sanchez


ICE-Guided LAA Closure: Why? How?

Vivek Reddy

Device-Related Thrombus & Pre/Peri/Post-Implant Anticoagulation

Johannes Brachmann



Watchman Implantation – Case 2

Broadcast from Mount Sinai Hospital
Operators: Srinivas Dukkipati and Jacob Koruth
Panel: Jose Mauricio Sanchez, Johannes Brachmann, Vijay Swarup, Boris Schimdt, Vivek Reddy


Session VI - Other LAAC Technologies

Moderator: Miguel Valderrábano



Wavecrest: Introduction & Recorded Case

Tom De Potter


LAAC Potpourri – Watchman-Flex/Lifetech/Occlutech/Aegis/Prolipsis

Vivek Reddy

Atriclip: Introduction & Recorded Case

Andrea Natale


Managing Incomplete LAA Ligation

Arash Aryana

Lariat: Introduction & Recorded Case

David Wilber



Questions & Discussion

Tom De Potter, Andrea Natale, David Wilber, Vivek Reddy, Arash Aryana, Miguel Valderrábano


Session VII – Putting it All Together

Moderators: Francis Marchlinski and Andrea Natale

The Munich Expert Consensus Document on LAA closure

Thorsten Lewalter


Cost Effectiveness of LAA Closure

Sheldon Singh


Debate: Stroke Prevention in the 78 yo Diabetic Woman After Catheter Ablation for AF

Oral Anticoagulation Therapy

Peter Kowey


LAA Suture Ligation

Randall Lee

Left Atrial Appendage Closure

Lucas Boersma


Nothing Else Required

Gerhard Hindricks

Questions & Discussion

Thorsten Lewalter, Sheldon Singh, Peter Kowey, Lucas Boersma, Randall Lee,
Gerhard Hindricks, Francis Marchlinski, Andrea Natale


Cardiac Rhythm Management

Commercial Support

A special thank you to the following companies for their generous support:

Boston Scientific

Biosense Webster, Inc.

Daiichi Sankyo, Inc.

St. Jude Medical


SentreHEART, Inc.


Janssen Pharmaceuticals, Inc.

Bristol-Meyers Squibb


MediaSphere Medical, LLC



Program Director

Vivek Reddy, MD
The Mount Sinai Hospital
New York, NY



Arash Aryana, MD
Regional Cardiology Associates
Sacramento, CA

Lucas Boersma, MD, PhD
St. Antonius Hospital
Nieuwegein, The Netherlands

Johannes Brachmann, MD
Hospital Klinikum Coburg
Coburg, Germany

Tom De Potter, MD
OLV Hospital
Aalst, Belgium

Luigi Di Biase, MD, PhD
Albert Einstein College of Medicine
Bronx, NY

John Camm, MD
St. George's University of London
London, England

Andre d’Avila, MD, PhD
Hospital Cardiologico
Santa Catarina, Brazil

Shephal Doshi, MD
Pacific Heart Institute
Santa Monica, CA

Srinivas Dukkipati, MD
The Mount Sinai Hospital
New York, NY

Christopher Ellis, MD
Vanderbilt Heart and Vascular Institute
Nashville, TN

Michael Ezekowitz, MD
Jefferson Medical College
Wynnewood, PA

Gerhard Hindricks, MD
University of Leipzig
Leipzig, Germany


Jacob Koruth, MD
The Mount Sinai Hospital
New York, NY

Peter Kowey, MD
Main Line Health System
Wynnewood, PA

Dhanunjaya Lakkireddy, MD
Mid-America Cardiology at University of Kansas Hospital
Kansas City, KS

Randall Lee, MD, PhD
University of California San Francisco
San Francisco, CA

Thorsten Lewalter, MD
Isar Heart Center Munich
Munich, Germany

Daniel Lustgarten, MD
The University of Vermont Medical Center
Burlington, VT

Moussa Mansour, MD
Massachusetts General Hospital
Boston, MA

Francis Marchlinski, MD
University of Pennsylvania Hospital
Philadelphia, PA

Nassir Marrouche, MD
University of Utah Health Sciences Center
Salt Lake City, UT

Marc Miller, MD
The Mount Sinai Hospital
New York, NY

Carlos Morillo, MD
McMaster University
Hamilton, ON, Canada

Andrea Natale, MD
Texas Cardiac Institute
Austin, TX


Petr Neuzil, MD, PhD
Homolka Hospital
Prague, Czech Republic

Jeremy Ruskin, MD
Massachusetts General Hospital
Boston, MA

Jose Mauricio Sanchez, MD
Mercy Clinic Heart & Vascular - Ballas – Olive
Saint Louis, MO

Boris Schmidt, MD
Cardioangiologisches Centrum Bethanien
Frankfurt, Germany

Horst Sievert, MD
Frankfurt Cardiovascular Center
Frankfurt, Germany

Daniel Singer, MD
Massachusetts General Hospital
Boston, MA

Sheldon Singh, MD
Sunnybrook Health Sciences Center
Toronto, Canada

Vijay Swarup, MD
Arizona Heart Rhythm Institute
Phoenix, AZ

Claudio Tondo, MD, PhD
Centro Cardiologico Monzino-University of Milan
Milan, Italy

Miguel Valderrábano, MD
Methodist DeBakey Cardiology Associates
Houston, TX

David Wilber, MD
Loyola University Chicago Stritch School of Medicine
Chicago, IL




Objectives & Target Audience

Target Audience

This activity has been developed to meet the educational needs of electrophysiologists, cardiologists, surgeons, and other physicians and associated healthcare professionals with an interest in the management of stroke in AF patients.

Learning Objectives

Upon completion of this activity, participants will be able to:

  • Discuss the role of the LAA in AF-related strokes.
  • Evaluate pharmacological and interventional therapeutic approaches for stroke prophylaxis in AF.
  • Examine randomized clinical trial and registry data.
  • Review appropriate NOACC and LAA closure patient selection criteria.
  • Assess the cost-effectiveness of LAA closure therapy.
  • Evaluate optimal LAA closure clinical decision making strategies and procedural approaches.
  • Examine therapeutic approaches for stroke prevention post catheter ablation for paroxysmal AF.
  • Review antiarrhythmic effects of LAA exclusion.


This activity is designed to serve as a learning experience on evaluating optimal evidence-based treatment approaches for stroke prophylaxis in Atrial Fibrillation patients, and is not accredited for continuing medical education credits.

Cardiac Rhythm Management